Ovarian metastases of ileal neuroendocrine tumor

A 55-year-old, menopausal woman with history of breast carcinoma was referred for recurrent abdominal pain without diarrhea. Physical examination, routine biological investigation, and serum CA15-3 were normal. Abdominal contrast-enhanced computed tomography (CT) found a 15-mm ileal hyper-vascularized lesion mild intestinal dilation mesenteric mass about 20 mm. Both ovaries moderately enlarged radiological overt signs malignancy. CT findings consistent neuroendocrine tumor (ileal-NET) invasion. Serum value chromogranin 18F-Fluorodihydroxyphenylalanine (18F-FDOPA) positron emission (PET)/CT added to the preoperative work-up 1 Addeo P. Poncet G. Goichot B. et al. The diagnostic 18F-fluorodihydroxyphenylalanine PET/CT in small bowel tumors. J Gastrointest Surg. 2017; 22: 722-730 Crossref PubMed Scopus (7) Google Scholar distinctly identified primary ileal-NET involvement. Moreover, intense pathological 18F-FDOPA uptake shown both peritoneal nodule few millimeters Douglas space (Fig 1, A), suggesting ovarian metastases carcinomatosis. Surgical exploration that removed by 20-cm resection lymphadenectomy. Intervention completed bilateral salpingo-oophorectomy, omentectomy, multiple biopsies B). Postoperative course uneventful, pathology confirmed 20-mm, well-differentiated grade-2 (Ki-67: 4%) invasion, spread, pelvic as size (pT4N2M1, UICC 2016).